The frequency floor is the same one that applies to everyone. The Physical Activity Guidelines for Americans say adults should do muscle-strengthening activities of moderate or greater intensity and that involve all major muscle groups on 2 or more days a week (Physical Activity Guidelines for Americans, 2nd edition, HHS, 2018).
ACSM repeats the two days and then tailors the rest to the goal. Its 2026 position stand gives a higher weekly volume of about 10 sets per muscle group for muscle growth, and heavier loads at 80% of one-repetition maximum for 2 to 3 sets per exercise for strength (ACSM, Resistance Training Prescription for Muscle Function, Hypertrophy, and Physical Performance in Healthy Adults: An Overview of Reviews, Medicine & Science in Sports & Exercise, announced March 17, 2026). One of its authors, Stuart Phillips, put the priority as training all major muscle groups at least twice a week rather than chasing the idea of a perfect or complex training plan (ACSM, 2026).
The stand also takes several things off the required list. It reports that training to fatigue or momentary muscle failure, the choice between machines and free weights, and complex periodization did not consistently impact outcomes for the average healthy adult, and that elastic bands, bodyweight exercises, and home-based routines yield marked benefits in strength, hypertrophy, and physical function (ACSM, 2026).